Research


Biomet has a significant amount of research available pertaining to orthopaedic devices, techniques and treatments. Information contained in the following articles may contain in-vitro, preclinical or clinical data which have not been reviewed, approved or cleared by the Food and Drug Administration (FDA) or information that is inconsistent with the approved product labeling. This information is being made available to health care practitioners for educational and scientific purposes only. It is Biomet's intent to provide information that helps to better understand the various technologies of our industry. To request such information, please complete the electronic form below or email us directly at contactebi@ebimedical.com

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BONE HEALING TECHNOLOGIES
191111L The Conservative Treatment of Osteonecrosis for the Femoral Head (Aaron) Clinical Ortho. & Related Research, Dec. 1989
191327L Acceleration of Experimental Endochrondral Ossification by Biophysical Stimulation of the Progenitor Cell Pool (Aaron & McK Ciombor) Jrl of Ortho Research, Vol. 14,, No. 4, 1996
191189L Stimulation of Experimental Endochondral Ossification by Low-Energy Pulsing Electromagnetic Fields (Aaron & Jolly) JBJS, 1989
191174L Intramedullary Fixation for Congenital Pseudarthrosis of the Tibia (Baker, Cain & Tulllos) JBJS, Feb. 1992
191106L Long-Term Pulsed Electromagnetic Field (PEMF) Results in Congenital Pseudarthrosis. (Basset-Ascani) Calcified Tissue International 1991
191136L Treatment of Ununited Tibial Diaphyseal Fractures with Pulsing Electromagnetic Fields (Bassett), JBJS, April 1981
191149L Treatment of Therapeutically Resistant Non-unions with Bone Grafts & Pulsing Electromagnetic Fields (Bassett) JBJS, Oct. 1982
191166L PEMF Treatment in Ununited Fractures and Failed Arthrodeses (Bassett, Mitchell, & Gaston) Journal of Amer. Med. Assoc., Feb. 5, 1982
191180L Effects of Pulsed Electromagnetic Fields on Steinberg Ratings of Femoral Head Osteonecrosis (Bassett) Clinical Ortho. & Related Research, Sept. 1989
191144L Pulsed Eelctromagnetic Fields in the Treatment of Scaphoid Nonunions (Beckenbaugh) ABSTRACT, April 1985
191319L Electrical Stimulation of Human Femoral Intertrochantric Osteotomies: Double-Blind Study (Borsalino, Bagnacani, et al) Clinical Ortho & Related Research, No. 237, Dec. 1988
191145L A New Treatment for Charcot Joint in the Diabetic Foot (Estersohn) Journal of Podiatric Medicine, Feb. 1987
191141L The Use of PEMFs to Achieve Arthrodeses of the Knee following Failed Total Knee Arthroplasty (Bigliana, Schink, & Bassett) JBJS, 1983
191183L Electrochemical Aspects of DC Stimulation of Osteogenesis, (Black, Baranowski & Brighton). Bioelectrochemistry & Bioenergetics, 1984
191284L Tibial Nonunion Treated with Direct Current Capacitive Coupling or Bone graft (Brighton, Shaman, Heppenstall, et al) Clinical Ortho. Dec. 1995
191172L The Bone Growth Chamber for Quantification of Electrically Induced Osteogenesis. (Buch, Albrektsson & Herbst) Journal of Ortho. Research, 1986
191186L Direct Current Influence on Bone Formation in Titanium Implants (Buch, Herbst, Albrektsson) Biomaterials, 1984
191225L Totally Implanted Direct Current Stimulator as Treatment for a Nonunion in the Foot. (Cohen DPM, Roman, DPM, Lovins, DPM) The Journal of Foot & Ankle Surgery. Vol 32, Num. 4 1993
191115L A Ten-Year Review of Treatment of Delayed Union & Nonunion with an Implanted BGS. (Cundy, Paterson) Clinical Ortho & Related Research Oct. 1990
191137L Treatment of Nonunited Scaphoid Fractures by Pulsed Electromagnetic Field and Cast (Frykman) Journal of Hand Surgery, May 1986
191187L Treatment of Ununited Tibial Fractures: A Comparison of Surgery & PEMF (Gossling, Abbott, & Bernstein) Ortho., June 1991
191262L Acceleration of Tibial Fracture Healing by Non-Invasive Low Intensity Pulsed Ultrasound (Heckman) JBJS, Jan. 1994
191239AL The Treatment of Delayed Unions & Nonunions of the Proximal Fifth Metatarsal with Pulsed Electromagnetic Fields (Holmes) Abstract from the 24th Annual Meeting of the American Ortho. Foot & Ankle Society, Feb. 1994
191239L Treatment of Delayed Union & Nonunion the Proximal Fifth Metatarsal with Pulsed Electromagnetic Fields (Holmes) Presented at the 24th Annual Meeting of The American Ortho. Foot & Ankle Society, Feb. 1994
191289L Ankle and Subtalar Fusion Utilizing A Tricortical Bone Graft, Bone Stimulator and External Fixator After Avascular Necrosis of the Talus (Janis, Krawetz, Wagner) The Jrnl of Foot and Ankle Surgery, Vol, 35, No. 2, 1996
191123L Osteogenesis Imperfecta - A Nonunion of the Femur in a Tarda Type! Patient Treated Successfully by Pulsing External Electrical Fields (Krempen) Journal of Neuro. & Ortho.Medicine, July 1986
191238L Osteochrondritis Disseans Noninvasive Treatment Using PEMFS (Lunch, Henning)
191124L Results of Pulsed Electromagnetic Fields in Ununited Fractures After External Skeletal Fixation ( Marcer, Musatti, Bassett) Clinical Orthopedics, Nov., 1984
191151L Treatment of Scaphoid Pseudarthrosis with Bone Grafting & PEMF (Melone & Pess) AAOS Handout, 1986
191326L Pulsating Electromagnetic Field Stimulates mRNA Expression of Bone Morphogenetic Protein -2 and -4 (M. Nagai and M. Ota) Jrl Dent Res Vol. 73, Oct. 1994)
191286AL Abstract: Effect of Exposure Time on Stimulation of Healing in the Rabbit Tibial Osteotomy Model by a Time Varying Pulsed Electromagnetic Field and by Combined Magnetic Fields (Nepola, Fredericks, Simon, Abbot)
191132L The Treatment of a Phalangeal Delayed Union Using Electrical Stimulation (Ohl) Orthopedics, April 1988
191140L Electrical Stimulation Applied to Bone and Nerve Injuries in the Upper Extremity (Osterman & Bora, Jr.) Ortho. Clinics of No. America July 1986
191118L Treatment of Congenital Pseudarthrosis of the Tibia with Direct Current 9timulation (Paterson) Clinical Ortho. & Related Research, May 1980
191131L Treatment of Delayed Union & Nonunion with an Implanted Direct Current Stimulator (Paterson) Clinical Ortho. & Related Research, May 1980
191133L Treatment of Nonunion with a Constant Direct Current: A Totally Implantable System (Paterson) Orthopedic Clinics of N. Amer., Jan. 1984
191173L Electrical Stimulation in the Treatment of Congenital Pseudarthrosis of the Tibia (Paterson & Simonis) British Bone & Joint, 1985
191201L The Dose Response relationship in PEMF Therapy of Ununited Fractures (Pethica & Brownell) Abstract from Biolelectrical Repari & Growth Society, Washington, D.C., October 9-12, 1988
191112L The Natural History & Treatment of Delayed Union Stress Fractures of the Anterior Cortex (Rettig) American Journal of Sports Medicine 1988
191317L Use of Implantable Direct Current Stimulation in Bone Grafter Foot & Ankle Arthodeses: A Retrospective Review J. Christopher Reynolds
191343L No Effect of Low Intensity Ultra Sound on Healing Time of Intramedcillary Fixed Tibial Fractures
191138L Prevention of Osteoporosis by PEMF, (Rubin) Journal of Bone & Joint, March 1989
191114L A Double Blind Trial of Pulsed Electromagnetic Fields for Delayed Union of Tibial Fractures (Sharrard) British Bone & Joint, May 1990
191288AL Abstract: A Double Blind Trial of PEMFs for Delayed Tibial Union: Clinical Follow Up (Sharrad) Presented at 16th Annual Meeting of the Bioelectromagnetics Society in Copenhagen, June, 1994
191263L Scaphoid Nonunion (Simionian, Trumble) Jrnl of AAOS, Vol.2, No.4, July/Aug. 1994
191126L A Review of Delayed Union of Open Tibia Fractures Treated with External Fixation and Compulsing Electromagnetic Field (Stein, Anzel) Orthopedics, March 1984
191182L Osteonecrosis of the Femoral Head (Steinberg, Brighton, Fallon) Clin. Ortho.& Related Research. May 1989
191119L Endothelial Cell Response to Pulsed Electromagnetic Fields: Stimulation of Growth Rate & Angiogenesis in Vitro (Yen-Patton) Journal of Cellular Physiology, 1988
191336L PEMFs Simultaneously Induce Osteogenesis and Upregulate Transcription of Bone Morphogenetic Proteins 2 and 4 in Rat Osteoblasts in Vitro (Bodamyali, Bhatt, Hughes, Winrow, Kanczler, Simon, Abbott, Blake and Stevens) Biochemical and Biophysical Research Communications, 1998
191339L Clinical Effects of Electormagnetic and Electric Fields on Fracture Healing (Ryaby) Clinincal Orthopedics and Related Research, 1998
IMPLANTABLE SPINAL FUSION STIMULATORS
191152L The Rate of Pseudarthrosis (Surgical Nonunion) in Patients Who Are Smokers & Patients Who Are Nonsmokers: A Comparison Study (Brown) Spine - Nov. 1986
196086L Classification of Pseudarthrosis of the Lumbar Spine (Heggness, et al) Spine Magazine, Vol, 15, No. 85, 1991
196083L Spine Update: Degenerative Lumbar Spondylolisthesis (Herkowitz) Spine Magazine, Vol, 20, No. 9), Nov. 1994
196026L The Efficacy of Direct Current Electrical Stimulation to Enhance Canine Spinal Fusions (Kahanovitz) Clin. Ortho. & Related Research, Feb. 1990
196069 The Effect of Electromagnetic Pulsing on Posterior Lumbar Spinal Fusions In Dogs. (Kahanovitz, Arnocxky, Nemzek, DPM, Shores, DPM) Spine, Vol, 19, Num. 6, March 1994
196071 The Effect of Postoperative Electromagnetic Pulsing on Canine Posterior Spinal Fusions. (Kahanovitz, Arnoczky) Spine, 1984
196127 The Role of Direct Current in the Critical Pathway for Lumbar Spinal Fusion (Kahanovitz Pathos) Jrnl of Care Mgmt. Dec. 1996, Vol. 2, No. 6
196024 Direct Current Electrical Bone Growth Stimulation for Spinal Fusion (Kane) Spine, March 1988
196088 Results of Lumbar Pseudarthrosis Repair (Lauerman) Jrnl of Spinal Disorders, Vol. 5 #2
196073 The Socioeconomic Effects of the SpF Implantable Spinal Fusion Stimulator in Lumbar Spinal Fusion (Levine) Jan. 1994
196085 Treatment of Degenerative Spondylolisthesis (Lombardi) Spine Magazine, Vol. 10, No. 9) June, 1985
196025 Stimulation of Bone Formation by Electrical Current on Spinal Fusion (Nerubay) From Chaim Sheba Med. Center, Israel, Jan. 1985
196130 Efficacy of Implantable Bone Growth Stimulation in Instrumental Lumbrosacral Spinal Fusion (Rogozinski & Rogozinski) Spine, Vol, 21, No. 21, Nov, 1996
196084 The Effect of Nicotine on Spinal Fusions (Silcox) Spine, Vol, 20 No. 14, Jan. 1995
196161L A controlled perspective outcome study of implantable electrical stimulation with spinal instrumentation in a high risk spinal fusion population (Kucharzyk) "Spine", Vol. 24, No. 5, March 1, 1999
196126 The Use of Implantable Direct Current Stimulation in Multi-Level Spinal Fusion without Instrumentation: A Prospective Clinical & Radiographic Evaluations with Long Term Follow-up (Tejano, Puno, Ignacio) Spine, Vol, 21, Aug. 15, 1996
196165L In Vivo evaluation of coralline hydroxyapatite and direct current Electrical stimulation in Lumbar Spinal Fusion (Bozic) Spine, Vol. 24, No 20, 1999
EXTERNAL FIXATION SYSTEMS
192072L The Callotasis Method of Limb Lengthening (Aldegheri)Clinical Ortho., April 1989
192086L Biomechanics of Ext. Fix. Part 1 (Aro-Chao) Surgical Rounds for Orthopedics, June 1990
192116L Unilateral External Fixation for Severe Pilon Fractures (Bonar & Marsh) Foot & Ankle, Feb. 1993
192151L Tibial Plafond Fractures: Changing Principles of Treatment (Bonar, Marsh) American Academy of Orthopaedic Surgeons, Vol.2, No.6
192069L The Effect of Rigidity on Fracture Healing in External Fixation (Chao) Clin. Ortho. & Related Research, April, 1988
192073L Limb Lengthening by Distraction of the Epiphyseal Plate (DeBastiani, et al.) British Bone & Joint, 1986
192241L New Technique for High Tibial Ostetomy: Distraction Valgus Osteotomy With External Fixator (Kramer, Raab, Kelikian, Goldstein)
192096L Upper Tibial Valgus Osteotomy Using a Dynamic External Fixator (Fowler, Gie & MacEachern) British Bone & Joint, July 1991
192180L External Fixation for Distal Radius Fractures Adverse Effects of Excess Distraction (Kaempffe) Amer. Jrnl. of Ortho. March 1996, Vol. XXV, No. 3
192196L Use of an Articulated External Fixator for Fractures of the Tibial Plafond (Marsh, Bonar, Nepola, Decoster, Hurwitz) JBJS Vol. 77-A, No. 10, Oct. 1995
192076L Treatment of Open Tibial Fractures with the Orthofix Fixator (Melendez) Clin. Ortho. & Related Research, April 1989
192121L Reconstruction of the Lower Extremity after Grade III Distal Tibial Injuries using Combined Microsurgical Free Tissue Transfer and Bone Transport by Distraction Osteosynthesis. (Oppenheim & Hutter) Annals of Plastic Surgery, Vol. 30 Num. 2 Feb. 1993
192067L The Treatment of Pediatric Fractures with Dynamic Azial External Fixation (price) Techniques Ortho., 1989
192141L Fixators & Mechanical Axis Realignment (Charles T. Price), Orthopaedic Clinics of N. America, Vol. 20, No. 3, July 1994
192114L Intra-Articular Fractures of the Distal Tibia: Surgical Management Limited Internal Fixation and Articulated Distraction. (Saleh, Shanahan & Fern) Injury Vol. 24, No. 1, 1993
192148L Dynamic Unilateral Distraction Fixation Surgical Management of Tibial Pilon Fractures (Treadwell, Fallat, DPM; Foot & Ankle Int'l, Vol. 33 No. 5 1994)
192131L A Randomized, Prospective Study Comparing the Complications Encountered in the Management of Pilon Fractures. (Wyrsch, McFerren) Journal of Ortho. Trauma Vol, 8, #3, 1994
192197L Operative Treatment of Fractures of the Tibial Plafond. A Randomized Prospective Study (Wyrsch, McFerran, McAndrew, Limbird, Harper, Johnson, Schwarz) JBJS, Vol. 78-A, No. 11, Nov. '96
192241L New Technique for High Tibial Osteotomy : Distraction Valgus Osteotomy with External Fixator (Kramer, Raab, Kelikian, Goldstein) Illinois Bone & Joint Institute
COLD THERAPY
199000L The Effect of Cold Therapy on Morbidity Subsequent to Arthroscopic Lateral Retinacular Release. Ortho Review - Sept. 91 (rev. 2/99)
199004L Constant Cold Therapy for Total Joint Replacements. (Ogden & Biser) Presented to Piedmont Ortho. Society, May 1990 (rev. 5/90)
199005L The Effects of Cold Therapy to Pain Parameters of Lumbar Surgical Patients. Study Performed at Med. Arts Hosp., Dallas, TX
199045L The Effect of Cold Therapy on the Postoperative Course of Total Hip & Knee Arthroplasty Patients (Scarcella & Cohn) American Jrnl of Orthopedics, Nov. 1995 (rev. 11/95)
199047L The Effect of Ice Application vs. Controlled Cold Therapy on Skin Temperature When Used with Postoperative Bulky Hand & Wrist Dressings: A Preliminary Study (Culp & Taras) Jrnl of Hand Therapy, Oct/Dec. 1995 (rev. 10-12/95)
199053L The Efficacy of Cryotherapy in the Postoperative Shoulder (Speer, Warren & Horowitz) Jrnl of Shoulder & Elbow, Vol, 5, No.1, Jan/Feb.1996 (rev. 1-2/96)
199061L Cold Therapy: Study Supports Portable Continuous Flow Study Supports Portable Continuous Flow (Barber, McGuire) Biomechanics, June 1988 (rev. 6/98)
199062L Controlled Outcome Study of Cold Therapy in Spinal Fusion Patients (Kucharzyk)
SPORTS MEDICINE
203018L Ankle Joint Strength, Total Work and ROM: Comparison Between Prophylactic Devices (Gehlsen, Pearson, Bahamonde) Athletic Training, JNATA, Vol. 26, Spring 1991
203029L Heel Pain Control Characteristics of the Active Ankle Brace (Siegler, Liu)
203030L The Three Dimensional Passive Support Characteristics of Ankle Braces (Siegler, Liu, et al) Presented - 1996 Amer. College of Foot & Ankle Surgeons Mtg and Seminar